Anti-Malarial Medication - Prevention

The choice of anti-malarial medication will depend on where you are going, the type of trip you have planned, any medical conditions and allergies. NO ANTI-MALARIAL MEDICATION IS 100% EFFECTIVE.

It is essential to take precautions against mosquito bites






Nausea or indigestion

Vaginal or oral thrush

Sunburn and sun sensitivity

Rash or itching

90% effective in malarial areas

Provides protection against skin infections and some intestinal infections

Carry anti-thrush cream if you have a history of thrush

Causes photosensitivity- use sunscreen

Contraindicated in children and pregnant women

Take one tablet daily with food

Start one day before you enter malarial area and continue for 28 days after leaving the area.

Stay upright (sitting or standing) for 2 hours after taking tablet


Headache and dizziness

Nausea and loss of appetite

Rash, aching muscles or weakness

Vivid dreams

Depression and anxiety

Fits and psychosis (rare)

90% effective in majority of malarial areas

Weekly tablet easier for long term travel

Can be used in second and third trimesters of pregnancy, and is safe in children

Trial period recommended

Not recommended for pilots, SCUBA divers or people operating dangerous machinery

Contraindicated for people with cardiac conduction disturbance, seizure disorders, and history of depression or other mental illness

Take one tablet weekly after your main meal. Start taking _______ week/s before arriving in malarial and take one per week on the same day whilst there. Continue to take for 4 weeks after leaving the area.

Avoid drinking alcohol on the day and the day after the tablet



Headache, dizziness and nausea

Blurred vision

Itchy skin

Hair loss


Few side effects

Safe for use by pregnant women and children

Less effective in Africa and South-East Asia

May make psoriasis worse

Contraindicated for people with seizure disorders

Take 2 tablets weekly with food on the same day every week starting 2 weeks before arriving in malarial area, weekly while there and continue for 4 weeks after leaving malarial area


Nausea and abdominal discomfort


Over 90% effective in all malarial areas

Few side effects

Safe for use in children

Higher cost

Not for use in pregnant or breastfeeding women

Cannot be used if patient has severe renal impairment

Take one tablet daily with food

Start one day before entering malarial area, continue taking one tablet daily whilst there and continue for seven days after leaving malarial area


If not on preventative tablets, self treatment should be considered if travelling to remote areas where medical attention is not readily available. If symptoms develop and there is no medical access for 24 hours you should start to treat yourself immediately.

Long term travellers to remote areas should also consider taking malaria testing kits.

RIAMET (CO-ARTEM) : Take 4 tablets when diagnosed, then 4 tablets at 8, 24, 36, 48 and 60 hours thereafter.

Take with meals to maximize absorption.

MALARONE : Take 4 tablets daily for 3 days. Malarone should be taken with food to maximize absorption.

CHLOROQUINE: Still an effective and cheap treatment for malaria in some areas but chloroquine resistance is now widespread in many parts of the world. If you have been treated with chloroquine and symptoms do not improve, seek further medical care. It is often used as a first line treatment in Africa as it is cheap and available.

LARIAM (MEFLOQUINE): 2 tablets to start then another 2 tablets 6 hours later but there is a high risk of side effects, especially nausea.

QUININE : An effective treatment, but should be used in hospitalised patients only.

Avoid FANSIDAR as most malaria is resistant to this. Avoid HALFAN (HALOFANTRINE) due to dangerous side effects